Preheat oven to 300°F (150°C) and line a baking sheet with parchment paper.
Melt the unsalted butter in a saucepan or microwave. Stir in garlic powder (or minced garlic), parmesan cheese, parsley, salt, pepper, and red pepper flakes.
In a large bowl, place the Ritz crackers and pour the butter mixture over them. Gently toss until evenly coated.
Spread the coated crackers in a single layer on the prepared baking sheet.
Bake for 10-12 minutes or until golden brown. Let cool slightly before serving.