Combine Ingredients: Begin by melting the butter in a skillet over medium heat and adding cream cheese, pumpkin puree, sweetened condensed milk, and pumpkin pie spice together. Stir constantly until the mixture thickens and becomes well-combined. Once blended smoothly, stir in graham cracker crumbs and white chocolate chips until everything is melted and smooth; if desired, add orange food coloring to create vibrant truffles.
Cool the Mixture: Continue stirring until the mixture releases from the sides of the pan when stirred. Once ready, pour the mixture onto a butter-greased baking sheet and spread it into an even layer.
Chill Until Firm: Refrigerate the sheet with your pumpkin cheesecake mixture until firm—this usually takes about 2 hours but can be left overnight for convenience.
Roll into Balls: After chilling, rub some butter on your hands to prevent sticking then take spoonfuls of the chilled dough and roll them into small balls between your palms.
Coat with Sugar: Pour granulated sugar into a shallow bowl and roll each ball in it until fully coated.
Add Finishing Touches: Using a toothpick or similar tool, create ridges along each truffle resembling pumpkin lines; then top with chocolate chips for an adorable look that mimics stems on pumpkins.